Natural-Looking Cheek Rejuvenation: How Ariessence® Peptides Offer an Alternative to Filler

Feb 12, 2026
The world of aesthetics is seeing an exciting explosion in regenerative treatments that offer more than just a quick fix. Here, we review how Ariessence® peptides can rejuvenate aging cheeks.

The goal of most anti-aging products and services is to reduce the years to rediscover a more youthful version of yourself that’s becoming suppressed by the aging process.

At Skin Shop MedSpa, our team offers a variety of services, from efficient and straightforward cosmetic injectables to more complex laser procedures. There’s a lot to choose from. 

While these treatments are effective, many of our clients are leaning toward regenerative procedures that work with the body to deliver longer-lasting and more natural results. In response, our team leaders — Dr. Tiffany Su and Dr. Hui “He” Kang — are answering the call with treatments like Ariessence® Pure PDGF+ peptide and collagen therapy, which relies on platelet-derived growth factors (PDGF) to reboot your skin on a cellular level.

Here, we review how to breathe new life into sunken and sagging cheeks with PDGF+, which the American Academy of Facial Aesthetics refers to as the new frontier in facial injectables.

Restoring volume in the cheeks

Aging doesn't simply boil down to wrinkles — many other processes occur below the surface of your skin that contribute to your increasingly older appearance. One of these processes is a shift in the thin layer of fat and muscles below your skin, which can rob you of those youthful, plump cheeks, leaving hollowed-out cheeks in its wake.

One of the go-to tools for restoring volume in cheeks has been dermal fillersnearly 10 million filler treatments are performed each year in the United States to fill out thinning lips, plump up sunken cheeks, and much more.

While we’re still thrilled with all that we can do with dermal fillers, we’re finding that Ariesse Pure PDGF+ can also play a role in this area. 

The power of platelets

Platelets have infiltrated various medical specialties as a promising regenerative treatment that can improve everything from joint health to hair loss. This assurance is because platelets are essential in the healing and regeneration functions of our bodies, thanks to their ability to utilize growth factors.

One of the issues with platelet-rich plasma (PRP) therapy, however, is that results can vary because the quality and number of platelets depend upon each person’s unique makeup.

With Ariesse, we don’t harvest platelets from your own blood — instead, we use platelet-derived growth factors, including:

  • Epidermal growth factors
  • Transforming growth factors
  • Vascular endothelial growth factors

In plainspeak, PDGF fully supports regeneration and repair at the cellular level by introducing the key proteins needed to boost the health of your skin.

Ariesse is a pharmaceutical-grade PDGF, with concentration levels up to 300,000 times that of growth factors of aesthetic products.

PDGF+ and your cheeks

When it comes to your cheeks, we can apply Ariesse PDGF+ as a topical solution, which is another great benefit — it’s non-invasive.

This powerful solution penetrates your skin, releasing growth factors that accelerate cellular turnover. These growth factors also promote better vascularization, providing your cheeks with easier access to regenerative resources that keep them looking youthful and healthy.

Explore why Ariesse PDGF+ is the next generation of skin rejuvenation. Contact our office in Houston, Texas, at 713-701-1717 today. Or, use the booking feature on our website to schedule an appointment.